Recombinant Human MED30 / TRAP25 protein (ab164823)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTME IFQLLRNMQLPNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCN ENCGGMDPIPVEQLIPYVEEDGSKNDDRAGPPRFASEERREIAEVNKKLK QKNQQLKQIMDQLRNLIWDINAMLAMRN
    • Amino acids
      1 to 178
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164823 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • MED30
    • MED30_HUMAN
    • Mediator complex subunit 30
    • Mediator of RNA polymerase II transcription subunit 30
    • THRAP6
    • Thyroid hormone receptor-associated protein 6
    • Thyroid hormone receptor-associated protein complex 25 kDa component
    • TRAP/Mediator complex component TRAP25
    • Trap25
    see all
  • Function
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • Tissue specificity
    Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
  • Sequence similarities
    Belongs to the Mediator complex subunit 30 family.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • ab164823 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164823 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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