Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceAPLD SVHQDDHSLR ESMIQLAEGL ITGTVLTQFD QLYRKKPGMT MSCAKLPQNI SKNRYRDISP YDATRVILKG NEDYINANYI NMEIPSSSII NQYIACQGPL PHTCTDFWQM TWEQGSSMVV MLTTQVERGR VKCHQYWPEP TGSSSYGCYQ VTCHSEEGNT AYIFRKMTLF NQEKNESRPL TQIQYIAWPD HGVPDDSSDF LDFVCHVRNK RAGKEEPVVV HCSAGIGRTG VLITMETAMC LIECNQPVYP LDIVRTMRDQ RAMMIQTPSQ YRFVCEAILK VYEEGFVKPL TTSTNK
    • Amino acids637 to 926

Specifications

Our Abpromise guarantee covers the use of ab42576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific Activity: 10 U/ug. One unit will hydrolyze 1 nmol p-nitrophenyl phosphate per minute at pH 7.4 and 30C. Assay buffer: 50 mM HEPES, pH 7.4, 2 mM EDTA, 3 mM DTT, 100 mM NaCl, 50 mM pNPP.
  • Applications

    Inhibition Assay

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 75% Sodium chloride, 50% Glycerol, 0.05% Tween 20, 25mM Tris HCl, 2mM EDTA, 10mM Glutathione, 1mM DTT, pH 8

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • MEG
    • megakaryocyte phosphatase
    • megakaryocyte protein-tyrosine phosphatase
    • Protein tyrosine phosphatase MEG1
    • Protein tyrosine phosphatase, megakaryocyte
    • protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
    • Protein-tyrosine phosphatase MEG1
    • PTN4
    • PTN4_HUMAN
    • PTPase MEG1
    • PTPase-MEG1
    • PTPMEG
    • PTPMEG1
    • Ptpn4
    • Tyrosine protein phosphatase non receptor type 4
    • Tyrosine-protein phosphatase non-receptor type 4
    see all
  • FunctionMay act at junctions between the membrane and the cytoskeleton.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 FERM domain.
    Contains 1 PDZ (DHR) domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localizationCell membrane. Cytoplasm, cytoskeleton.
  • Information by UniProt

References for Recombinant human MEG1 protein (ab42576)

ab42576 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab42576.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"