Recombinant Human Melanoma Inhibitory Activity protein (ab49847)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MGPMPKLADR KLCADQECSH PISMAVALQD YMAPDCRFLT IHRGQVVYVF SKLKGRGRLF WGGSVQGDYY GDLAARLGYF PSSIVREDQT LKPGKVDVKT DKWDFYCQ

Specifications

Our Abpromise guarantee covers the use of ab49847 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Endotoxin level
    < 0.100 Eu/µg
  • Purity
    > 95 % SDS-PAGE.
    Greater than 98% by SDS-PAGE and HPLC analyses.
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

  • Reconstitution
    Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

General Info

  • Alternative names
    • Cartilage derived retinoic acid sensitive protein
    • CD RAP
    • CDRAP
    • Melanoma derived growth regulatory protein precursor
    • Melanoma inhibitory activity protein
    • Melanoma-derived growth regulatory protein
    • Mia
    • MIA_HUMAN
    see all
  • Function
    Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
  • Tissue specificity
    All malignant melanoma cell lines tested and infrequently in glioma cell lines.
  • Sequence similarities
    Belongs to the MIA/OTOR family.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    May possess two intramolecular disulfide bonds.
  • Cellular localization
    Secreted.
  • Information by UniProt

References for Recombinant Human Melanoma Inhibitory Activity protein (ab49847)

ab49847 has not yet been referenced specifically in any publications.

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