Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L
    • Molecular weight
      12 kDa
    • Amino acids
      20 to 119
    • Additional sequence information
      MIA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain consisting of 101 amino having a total molecular mass of 11.5 kDa.

Specifications

Our Abpromise guarantee covers the use of ab117681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    HPLC

    SDS-PAGE

  • Purity
    > 97 % SDS-PAGE.
    Purified by proprietary chromatographic techniques. Greater than 97.0% pure determined by RP-HPLC and by SDS-PAGE.
  • Form
    Lyophilised
  • Additional notes
    Lyophilized MIA2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ab117681 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 7.40
    Constituents: 0.88% Sodium chloride, 98% Phosphate Buffer

  • Reconstitution
    It is recommended to reconstitute the lyophilized MIA2 in sterile ultra pure water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

General Info

  • Alternative names
    • FLJ22404
    • Melanoma inhibitory activity 2
    • Melanoma inhibitory activity protein 2
    • Mia2
    • MIA2_HUMAN
    see all
  • Function
    May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage.
  • Tissue specificity
    Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis.
  • Sequence similarities
    Belongs to the MIA/OTOR family.
    Contains 1 SH3 domain.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab117681 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab117681.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up