Recombinant Human MIRO1 protein (ab163047)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
Description
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Product name
Recombinant Human MIRO1 protein -
Expression system
Wheat germ -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPER VPTHIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPL INERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIETCVECSAK NLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDN DGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKG FLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTE LNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVC TNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVT VTRDKKIDLQKKQTQRNVFRCNVIGVKNCGKSGVLQALLGRNLMRQKKIR EDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEIICDVVCLVYDVSN PKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPTDFCRKHK MPPPQAFTCNTADAPSKDIFVKLTTMAMYPHARLRCMCTCNRCTFCICQN FLNSDLLQSVKNKIFTAVLNRHVTQADLKSSTFWLRASFGATVFAVLGFA MYKALLKQR -
Amino acids
1 to 659 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab163047 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- ARHT 1
- ARHT1
- FLJ11040
see all -
Function
Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. -
Tissue specificity
Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. -
Sequence similarities
Belongs to the mitochondrial Rho GTPase family.
Contains 2 EF-hand domains.
Contains 2 Miro domains. -
Cellular localization
Mitochondrion outer membrane. Colocalizes with MGARP and RHOT2 at the mitochondria. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (1)
ab163047 has been referenced in 1 publication.
- Hsieh CH et al. Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models. Cell Metab 30:1131-1140.e7 (2019). PubMed: 31564441