Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionQ02779
    • SpeciesHuman
    • SequenceFPRLPDPQALFPARRRPPEFPGRPTTLTFAPRPRPAASRPRLDPWKLVSF GRTLTISPPSRPDTPESPGPPSVQPTLLDMDMEGQNQDSTVPLCGAHGSH
    • Molecular weight37 kDa including tags
    • Amino acids855 to 954

Specifications

Our Abpromise guarantee covers the use of ab116847 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • M3K10_HUMAN
    • MAP3K 10
    • Map3k10
    • MEKK10
    • Mitogen activated protein kinase kinase kinase 10
    • Mitogen-activated protein kinase kinase kinase 10
    • Mixed lineage kinase 2
    • MKN28 derived nonreceptor type serine/threonine kinase
    • MKN28 kinase
    • MLK 2
    • MST
    • Protein kinase MST
    see all
  • FunctionActivates the JUN N-terminal pathway.
  • Tissue specificityExpressed in brain and skeletal muscle.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.
  • Information by UniProt

Recombinant Human MLK2 protein images

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116847 at approximately 36.63 kDa.

References for Recombinant Human MLK2 protein (ab116847)

ab116847 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116847.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"