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Recombinant Human MMP22 protein (denatured)
Recombinant Human MMP22 protein
Amino Acid Sequence
MGSSHHHHHHSSGLVPRGSHMGSYTLTPARLRWDHFNLTYRILSFPRNLL SPRETRRALAAAFRMWSDVSPFSFREVAPEQPSDLRIGFYPINHTDCLVS ALHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGPTRYSWKKGVWLTDL VHVAAHEIGHALGLMHSQHGRALMHLNATLRGWKALSQDELWGLHRLYG
23 kDa including tags
79 to 254
His tag N-Terminus
Additional sequence information
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 0.32% Tris HCl, 10% Glycerol, 2.4% Urea
- Matrix metallopeptidase 21
- matrix metallopeptidase 23B
Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
Predominantly expressed in ovary, testis and prostate.
Belongs to the peptidase M10A family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
Proteolytic cleavage might yield an active form.
Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
Information by UniProt
SDS-PAGE - Human MMP22 protein fragment (ab180279)
15% SDS-PAGE analysis of ab180279 (3μg).
has not yet been referenced specifically in any publications.
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