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Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- Matrix metallopeptidase 21
- Matrix metallopeptidase 23A
Protease. May regulate the surface expression of some potassum channels by retaining them in the endoplasmic reticulum.
Predominantly expressed in ovary, testis and prostate.
Belongs to the peptidase M10A family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
The toxin-like domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4.
Proteolytic cleavage might yield an active form.
Endoplasmic reticulum membrane. Membrane. A secreted form produced by proteolytic cleavage may also exist.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"