Recombinant Human MNK1 protein (ab62572)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 70% SDS-PAGE
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, WB
Description
-
Product name
Recombinant Human MNK1 protein
See all MNK1 proteins and peptides -
Purity
> 70 % SDS-PAGE.
Affinity purified. -
Expression system
Baculovirus infected Sf9 cells -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Actual molecular weight
74 kDa including tags -
Amino acids
2 to 465 -
Modifications
mutated T385D -
Tags
GST tag N-Terminus -
Additional sequence information
Deletion a.a. 165-205.
-
Specifications
Our Abpromise guarantee covers the use of ab62572 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
Functional Studies
Western blot
-
Form
Liquid -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.0462% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.395% Tris HCl, 0.05% Tween, 50% Glycerol (glycerin, glycerine), 0.58% Sodium chloride
General Info
-
Alternative names
- MAP kinase interacting kinase 1
- MAP kinase interacting serine/threonine kinase 1
- MAP kinase signal integrating kinase 1
see all -
Function
May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 1 protein kinase domain. -
Post-translational
modificationsDual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase. -
Cellular localization
Cytoplasm and Cytoplasm. Nucleus. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab62572 has not yet been referenced specifically in any publications.