Recombinant Human Monoacylglycerol Lipase protein (ab101045)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ99685
    • SpeciesHuman
    • SequenceMGSSHHHHHHSSGLVPRGSHMETGPEDPSSMPEESSPRRTPQSIPYQDLP HLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDL LVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLV LPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRV ERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHV LHKELPEVTNSVFHEINMWVSQRTATAGTASPP
    • Molecular weight36 kDa including tags
    • Amino acids1 to 333
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab101045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity> 85 % SDS-PAGE.
    purified by using conventional chromatography
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: 0% None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • EC 3.1.1.23
    • HU K5
    • HU-K5
    • HUK5
    • Lysophospholipase homolog
    • Lysophospholipase like
    • Lysophospholipase-like
    • MAGL
    • MGL
    • MGLL
    • MGLL_HUMAN
    • Monoacylglycerol lipase
    • Monoglyceride lipase
    see all
  • FunctionConverts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
  • Tissue specificityDetected in adipose tissue, lung, liver, kidney, brain and heart.
  • PathwayGlycerolipid metabolism; triacylglycerol degradation.
  • Sequence similaritiesBelongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.
  • Information by UniProt

Recombinant Human Monoacylglycerol Lipase protein images

  • ab101045 at 3 µg being analysed by 15% SDS PAGE.

References for Recombinant Human Monoacylglycerol Lipase protein (ab101045)

ab101045 has not yet been referenced specifically in any publications.

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