Recombinant Human Mortality Factor 4 like 2 protein (ab105615)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ15014
    • SpeciesHuman
    • SequenceMGSSHHHHHHSSGLVPRGSHMSSRKQGSQPRGQQSAEEENFKKPTRSNMQ RSKMRGASSGKKTAGPQQKNLEPALPGRWGGRSAENPPSGSVRKTRKNKQ KTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELK PWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCKKSQGNVDNKEYAVN EVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAPMSQVYGAPHLLR LFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVAS AEYHRKAL
    • Molecular weight34 kDa
    • Amino acids1 to 288
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab105615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity> 90 % SDS-PAGE.
    Purified using conventional chromatography.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • KIAA0026
    • MO4L2_HUMAN
    • MORF related gene X protein
    • MORF-related gene X protein
    • Morf4l2
    • MORFL2
    • Mortality factor 4 like protein 2
    • Mortality factor 4-like protein 2
    • MRGX
    • MSL3 2 protein
    • Protein MSL3-2
    • Transcription factor like protein MRGX
    • Transcription factor-like protein MRGX
    see all
  • FunctionComponent of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
  • Sequence similaritiesBelongs to the MRG family.
  • Cellular localizationNucleus.
  • Information by UniProt

Recombinant Human Mortality Factor 4 like 2 protein images

  • 15% SDS PAGE analysis of ab105615 (3 µg)

References for Recombinant Human Mortality Factor 4 like 2 protein (ab105615)

ab105615 has not yet been referenced specifically in any publications.

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