Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab89589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe Specific activity of ab89589 was determined to be 19 nmol/min/mg.
  • Applications

    SDS-PAGE

    Western blot

    Functional Studies

  • FormLiquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • cancer/testis antigen 96
    • CT96
    • Dual specificity protein kinase TTK
    • ECSTY kinase
    • ESK
    • FLJ38280
    • hMPS1
    • Monopolar Spindle 1 Like 1
    • MPH1
    • Mps 1
    • MPS1L1
    • Phosphotyrosine Picked Threonine Kinase
    • Phosphotyrosine picked threonine-protein kinase
    • PYT
    • RP3-357D13.2
    • ttk
    • TTK Protein Kinase
    • TTK_HUMAN
    see all
  • FunctionPhosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
  • Tissue specificityPresent in rapidly proliferating cell lines.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • Information by UniProt

Recombinant human Mps1 protein images

  • SDS-PAGE showing ab89589 at approximately 130kDa.
  • Kinase Assay demonstrating specific activity of ab89589.

References for Recombinant human Mps1 protein (ab89589)

ab89589 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89589.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"