Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab91344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityActivity: 1 nmol of ab91344 will reduce 2 nmol peptide-bound Met-S-sulfoxide in 1 min at 37°C.
    MetO-containing peptides are reduced by the enzyme in the presence of DTT.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.
    NiNTA purified
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 33% Glycerol, 0.1M Tris HCl, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Deafness, Autosomal Recessive 74
    • DFNB74
    • FLJ36866
    • Methionine R sulfoxide reductase B mitochondrial
    • Methionine sulfoxide reductase B3
    • Methionine-R-sulfoxide reductase B3
    • MsrB3
    • MSRB3_HUMAN
    see all
  • FunctionCatalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.
  • Tissue specificityWidely expressed.
  • Involvement in diseaseDeafness, autosomal recessive, 74
  • Sequence similaritiesBelongs to the MsrB Met sulfoxide reductase family.
    Contains 1 MsrB (methionine-R-sulfoxide reductase) domain.
  • Cellular localizationMitochondrion and Endoplasmic reticulum.
  • Information by UniProt

Recombinant human MSRB3 protein images

  • 0.5µg ab91344 on 12% SDS-PAGE gel.

References for Recombinant human MSRB3 protein (ab91344)

ab91344 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"