Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab91344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Activity: 1 nmol of ab91344 will reduce 2 nmol peptide-bound Met-S-sulfoxide in 1 min at 37°C.
    MetO-containing peptides are reduced by the enzyme in the presence of DTT.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    NiNTA purified
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 33% Glycerol, 0.1M Tris HCl, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Deafness, Autosomal Recessive 74
    • DFNB74
    • FLJ36866
    • Methionine R sulfoxide reductase B mitochondrial
    • Methionine sulfoxide reductase B3
    • Methionine-R-sulfoxide reductase B3
    • MsrB3
    • MSRB3_HUMAN
    see all
  • Function
    Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.
  • Tissue specificity
    Widely expressed.
  • Involvement in disease
    Deafness, autosomal recessive, 74
  • Sequence similarities
    Belongs to the MsrB Met sulfoxide reductase family.
    Contains 1 MsrB (methionine-R-sulfoxide reductase) domain.
  • Cellular localization
    Mitochondrion and Endoplasmic reticulum.
  • Information by UniProt

Images

  • 0.5µg ab91344 on 12% SDS-PAGE gel.

References

ab91344 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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