The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The protein sequence corresponds to Human MUC5B partial ORF ( XP_039877.9, 4186 a.a. - 4295 a.a.) and aa 5653-5762 on Uniprot Q9HC84 (http://www.uniprot.org/uniprot/Q9HC84).
Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Cervical mucin MUC5B
High molecular weight salivary mucin MG1
Mucin 5 subtype B, tracheobronchial
Mucin 5B oligomeric mucus/gel forming
Mucin-5 subtype B
Sublingual gland mucin
Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus.
Expressed on surface airway epithelia. Expressed mainly in mucous cells of submucosal glands of airway tissues. Highly expressed in the sublingual gland. Also found in submaxillary glands, endocervix, gall bladder, and pancreas.
The cysteine residues in the Cys-rich subdomain repeats are not involved in disulfide bonding.
Highly glycosylated. C-, N- and O-glycosylated. C-mannosylated in the Cys-rich subdomains probably on the first Trp residue of the WXXW motif. Highly O-glycosylated in the Ser/Thr-rich tandem repeat (TR) region. The repeat region is about 59% O-glycosylated with a high abundance of NeuAc(2)Hex(1)HexNac1-ol.