Overview

  • Product name
    Recombinant Human MUC7 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      41 kDa

Specifications

Our Abpromise guarantee covers the use of ab112727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    pH: 6.80
    Constituents: 1.58% Tris HCl, 3.09% DTT, 4% SDS, 0.2% Bromophenol blue, 20% Sucrose

  • Reconstitution
    Add 100ul of distilled water.

General Info

  • Alternative names
    • Apo MG2
    • Apo-MG2
    • DKFZp686J03256
    • FLJ27047
    • MG2
    • MGC34772
    • MUC 7
    • MUC-7
    • MUC7
    • MUC7_HUMAN
    • Mucin 7
    • Mucin 7, salivary
    • Mucin 7, secreted
    • Mucin-7
    • Salivary mucin 7
    • Salivary mucin-7
    see all
  • Function
    May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili.
  • Tissue specificity
    Expressed in salivary gland tissues and only in those that contain mucous acinar cells (e.g. sublingual and submandibular glands) and not in salivary glands containing only serous acinar cells (e.g. parotid gland).
  • Involvement in disease
    Genetic variations in MUC7 are associated with susceptibility to asthma (ASTHMA) [MIM:600807]. The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
  • Post-translational
    modifications
    N- and O-glycosylated. Contains fucose, mannose, galactose, N-acetylglucosamine and N-acetylgalactosamine.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab112727 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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