ReconstitutionAdd deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely.
Growth/differentiation factor 8
FunctionActs specifically as a negative regulator of skeletal muscle growth.
Involvement in diseaseDefects in MSTN are the cause of muscle hypertrophy (MSLHP) [MIM:614160]. MSLHP is a condition characterized by increased muscle bulk and strength. Affected individuals are exceptionally strong.
Sequence similaritiesBelongs to the TGF-beta family.