Recombinant Human Natriuretic Peptide Receptor A protein (ab112332)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      GVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHC FFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICS S
    • Molecular weight
      37 kDa including tags
    • Amino acids
      147 to 247
    • Tags
      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    useful for Antibody Production and Protein Array
  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • Form
    Liquid
  • Additional notes
    Best use within three months from the date of receipt of this protein. useful for Antibody Production and Protein Array
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Glutathione is reduced

General Info

  • Alternative names
    • ANP-A
    • ANPa
    • ANPR-A
    • ANPRA
    • ANPRA_HUMAN
    • Atrial natriuretic peptide A type receptor
    • Atrial natriuretic peptide receptor 1
    • Atrial natriuretic peptide receptor A
    • Atrial natriuretic peptide receptor type A
    • Atrionatriuretic peptide receptor A
    • GC A
    • GC-A
    • Guanylate cyclase
    • Guanylate cyclase A
    • GUC2A
    • GUCY2A
    • Natriuretic peptide A type receptor
    • Natriuretic peptide receptor A/guanylate cyclase A
    • NPR-A
    • NPR1
    • NPRA
    see all
  • Function
    Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
  • Sequence similarities
    Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    Contains 1 guanylate cyclase domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylation of the protein kinase-like domain is required for full activation by ANP.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • ab112332 run on a 12.5% SDS-PAGE Stained with Coomassie Blue.

References

ab112332 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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