Recombinant human Neurotrophin 3 protein (ab9792)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP20783
    • SpeciesHuman
    • SequenceMYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
    • Amino acids139 to 257

Specifications

Our Abpromise guarantee covers the use of ab9792 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

    Western blot

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Additional notesThe ED50, determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cultures was found to be in the range of 20-50 ng/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • HDNF
    • MGC129711
    • Nerve growth factor 2
    • Neurotrophic factor
    • Neurotrophin 3 precursor
    • Neurotrophin-3
    • Neurotrophin3
    • NGF 2
    • NGF-2
    • NGF2
    • NT 3
    • NT-3
    • NT3
    • NTF 3
    • NTF3
    • NTF3_HUMAN
    see all
  • FunctionSeems to promote the survival of visceral and proprioceptive sensory neurons.
  • Tissue specificityBrain and peripheral tissues.
  • Sequence similaritiesBelongs to the NGF-beta family.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant human Neurotrophin 3 protein images

  • Anti-Neurotrophin 3 antibody (ab65804) at 1 µg/ml + Recombinant human Neurotrophin 3 protein (ab9792) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 30 seconds

References for Recombinant human Neurotrophin 3 protein (ab9792)

This product has been referenced in:
  • Mantuano E  et al. The Unfolded Protein Response Is a Major Mechanism by Which LRP1 Regulates Schwann Cell Survival after Injury. J Neurosci 31:13376-85 (2011). Read more (PubMed: 21940431) »

See 1 Publication for this product

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Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4C for 1 week or -20C for future us...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"