Recombinant Human Neurotrophin 4 protein (denatured) (ab113151)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP34130
    • SpeciesHuman
    • Molecular weight14 kDa including tags
    • Amino acids81 to 210

Specifications

Our Abpromise guarantee covers the use of ab113151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 85 % SDS-PAGE.

  • FormLiquid
  • Additional notes


  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 2.4% Urea

General Info

  • Alternative names
    • GLC10
    • GLC1O
    • Neurotrophic factor 4
    • Neurotrophic factor 5
    • Neurotrophin 4
    • Neurotrophin 4/5
    • Neurotrophin 5
    • Neurotrophin 5 (neurotrophin 4/5)
    • Neurotrophin-4
    • Neurotrophin-5
    • Neutrophic factor 4
    • Neutrophic factor 5
    • NT 4
    • NT 4/5
    • NT 5
    • NT-4
    • NT-5
    • NT4
    • NT4/5
    • NT4P
    • NT5
    • NTF4
    • NTF4_HUMAN
    • NTF5
    see all
  • FunctionTarget-derived survival factor for peripheral sensory sympathetic neurons.
  • Tissue specificityHighest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
  • Involvement in diseaseDefects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
  • Sequence similaritiesBelongs to the NGF-beta family.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant Human Neurotrophin 4 protein (denatured) images

  • 15% SDS-PAGE showing ab113151 (3 µg) at approximately 14.1 kDa.

References for Recombinant Human Neurotrophin 4 protein (denatured) (ab113151)

ab113151 has not yet been referenced specifically in any publications.

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