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Source Escherichia coli
Amino Acid Sequence
Sequence MEPHSESNVPAGHTIPQVHWTKLQHSLDTALRRARSAPAAAIAARVAGQT RNITVDPRLFKKRRLRSPRVL FSTQPPREAADTQDLDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDS VSVWVGDKTTATDIKGKEVM VLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFV KALTMDGKQAAWRFIRIDTA CVCVLSRKAVR. Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 95
% SDS-PAGE. ab55441 is purified by chromatographic techniques.
Purity tested by SDS-PAGE and RP-HPLC.
Additional notes ab55441 can be dessicated and frozen at -18 centigrade for long term storage. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C.
Constituents: 50mM Sodium phosphate buffer, 150mM Sodium chloride, pH 7.2
Beta nerve growth factor
Beta-nerve growth factor
Function Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
Involvement in disease Neuropathy, hereditary sensory and autonomic, 5
Sequence similarities Belongs to the NGF-beta family.
Cellular localization Secreted.
Information by UniProt
References for Recombinant Human NGF protein (ab55441)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"