Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MRPLTEEETR VMFEKIAKYI GENLQLLVDR PDGTYCFRLH NDRVYYVSEK IMKLAANISG DKLVSLGTCFGKFTKTHKFR LHVTALDYLA PYAKYKVWIK PGAEQSFLYG NHVLKSGLGR ITENTSQYQG VVVYSMADIPLGFGVAAKST QDCRKVDPMA IVVFHQADIG EYVRHEETLT LEHHHHHH
    • Molecular weight
      22 kDa including tags
    • Amino acids
      1 to 180
    • Tags
      His tag C-Terminus
    • Additional sequence information
      NIP7 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 188 amino acids (1-180 a.a.) and having a molecular mass of 21.5kDa.

Specifications

Our Abpromise guarantee covers the use of ab119141 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    ab119141 was purified by proprietary chromatographic techniques.
  • Form
    Liquid
  • Additional notes
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names
    • 60S ribosome subunit biogenesis protein NIP7 homolog
    • CGI 37
    • CGI37
    • FLJ10296
    • HSPC031
    • HSPC180
    • KD93
    • NIP 7
    • NIP7
    • NIP7 nucleolar pre rRNA processing protein
    • NIP7_HUMAN
    • Nuclear import 7
    • Nuclear import 7 homolog
    • Nuclear import 7 homolog (S. cerevisiae)
    • OK/SW cl.76
    • OK/SW cl.78
    • OTTHUMP00000174889
    see all
  • Function
    Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
  • Tissue specificity
    Expressed in hematopoietic stem/progenitor cells.
  • Sequence similarities
    Belongs to the NIP7 family.
    Contains 1 PUA domain.
  • Cellular localization
    Nucleus > nucleolus.
  • Information by UniProt

References

ab119141 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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