The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 µg/µl.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
NKX2.5, mouse, homolog of
Cardiac-specific homeobox 1
Homeobox protein CSX
Homeobox protein NK-2 homolog E
Homeobox protein Nkx 2.5
Homeobox protein Nkx-2.5
NK2 homeobox 5
NK2 transcription factor related locus 5
NK2 transcription factor related, locus 5 (Drosophila)
NK2, Drosophila, homolog of, E
Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.
Expressed only in the heart.
Involvement in disease
Atrial septal defect 7, with or without atrioventricular conduction defects Tetralogy of Fallot Conotruncal heart malformations Hypothyroidism, congenital, non-goitrous, 5 Ventricular septal defect 3 Hypoplastic left heart syndrome 2 Asplenia, isolated congenital
Belongs to the NK-2 homeobox family. Contains 1 homeobox DNA-binding domain.