The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 µg/ul.
Best use within three months from the date of receipt of this protein.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Homeobox protein NK-3 homolog A
Homeobox protein Nkx 3.1
Homeobox protein Nkx-3.1
Homeobox protein Nkx3.1
NK homeobox (Drosophila) family 3 A
NK homeobox family 3 A
NK homeobox, family 3, member A
NK3 homeobox 1
NK3 transcription factor homolog A
NK3 transcription factor related locus 1
Nkx3.1, mouse, homolog of
FunctionTranscription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Tissue specificityHighly expressed in the prostate and, at a lower level, in the testis.
Sequence similaritiesBelongs to the NK-3 homeobox family. Contains 1 homeobox DNA-binding domain.
Post-translational modificationsUbiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.