Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. Regulates the stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.
Protein modification; protein glycosylation.
Belongs to the UPP synthase family.
Endoplasmic reticulum membrane. Colocalizes with Nogo-B during VEGF and wound healing angiogenesis.