Overview

  • Product nameRecombinant Human NPL protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ9BXD5
    • SpeciesHuman
    • SequenceMGSSHHHHHHSSGLVPRGSHMAFPKKKLQGLVAATITPMTENGEINFSVI GQYVDYLVKEQGVKNIFVNGTTGEGLSLSVSERRQVAEEWVTKGKDKLDQ VIIHVGALSLKESQELAQHAAEIGADGIAVIAPFFLKPWTKDILINFLKE VAAAAPALPFYYYHIPALTGVKIRAEELLDGILDKIPTFQGLKFSDTDLL DFGQCVDQNRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQM LEAFEQKDFSLALNYQFCIQRFINFVVKLGFGVSQTKAIMTLVSGIPMGP PRLPLQKASREFTDSAEAKLKSLDFLSFTDLKDGNLEAGS
    • Molecular weight37 kDa including tags
    • Amino acids1 to 320
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab106873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity> 95 % SDS-PAGE.
    ab106873 is purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • 0610033B02Rik
    • C112
    • C1orf13
    • Dihydrodipicolinate synthase
    • Dihydrodipicolinate synthetase homolog 1
    • MGC149582
    • MGC61869
    • N-acetylneuraminate lyase
    • N-acetylneuraminate pyruvate-lyase
    • N-acetylneuraminic acid aldolase
    • NAL
    • NALase
    • NPL
    • NPL_HUMAN
    • NPL1
    • RP11-249O6.1
    • Sialate lyase
    • Sialate-pyruvate lyase
    • Sialic acid aldolase
    • Sialic acid lyase
    see all
  • FunctionCatalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface.
  • Tissue specificityIsoform 2 is expressed in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocyte.
  • PathwayAmino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 1/5.
  • Sequence similaritiesBelongs to the DHDPS family. NanA subfamily.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Recombinant Human NPL protein images

  • 15% SDS-PAGE analysis of 3µg ab106873.

References for Recombinant Human NPL protein (ab106873)

ab106873 has not yet been referenced specifically in any publications.

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