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Source Escherichia coli
Amino Acid Sequence
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This protein has been shown to activate quinone based anti-tumor agents in vivo.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C.
Constituents: 8% PBS buffer salts, 2% Lactose
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitution Reconstitute the contents of the vial with 0.1ml water.
Cytochrome b 5 reductase
Function The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Sequence similarities Belongs to the NAD(P)H dehydrogenase (quinone) family.
Cellular localization Cytoplasm.
Information by UniProt
References for Recombinant human NQO1 protein (ab59663)
This product has been referenced in:
et al. Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation. PLoS One 10:e0119738 (2015).
Read more (PubMed: 25780921) »
See 1 Publication
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"