For the best experience on the Abcam website please upgrade to a modern browser such as
Amino Acid Sequence
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This protein has been shown to activate quinone based anti-tumor agents in vivo.
Concentration information loading... Preparation and Storage
Cytochrome b 5 reductase
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Belongs to the NAD(P)H dehydrogenase (quinone) family.
Information by UniProt
References for Recombinant human NQO1 protein (ab59663)
This product has been referenced in:
et al. Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation. PLoS One 10:e0119738 (2015).
Read more (PubMed: 25780921) »
See 1 Publication
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"