Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab82085 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    ab82085 contains no detectable proteases, DNase and RNase activity.
  • Applications

    SDS-PAGE

    EMSA

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • BD73
    • EAR 1R
    • EAR-1R
    • HZF2
    • Nr1d2
    • NR1D2_HUMAN
    • Nuclear receptor Rev ErbA beta variant 1
    • Nuclear receptor Rev ErbA beta variant 2
    • Nuclear receptor subfamily 1 group D member 2
    • Orphan nuclear hormone receptor BD73
    • Rev erb beta
    • Rev erba alpha related receptor
    • Rev-erb-beta
    • REVB
    • REVERBB
    • RVR
    • V-erbA-related protein 1-related
    see all
  • Function
    Binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3'. Acts as a potent competitive repressor of ROR alpha function.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab82085 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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