The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesBest use within three months from the date of receipt of this protein.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.31% Glutathione
alpha palindromic binding protein
Alpha palindromic-binding protein
locus control region factor 1
NFE2 related factor 1
Nuclear respiratory factor 1
FunctionTranscription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Tissue specificityUbiquitously expressed with strongest expression in skeletal muscle.
Sequence similaritiesBelongs to the NRF1/Ewg family.
Post-translational modificationsPhosphorylation enhances DNA binding.