Recombinant Human nSMase protein (ab114871)

Overview

  • Product nameRecombinant Human nSMase protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionO60906
    • SpeciesHuman
    • SequenceMKPNFSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEV WSEQDFQYLRQKLSPTYPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTL NGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHLHAEYNRQKDIYLA HRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDA YLETRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYI SCKSFETTTGFDPHSGTPLSDHEALMATLFVRHSPPQQNPSSTHGPAERS PLMCVLKEAWTELGLGMAQARWWATFASYVIGLGLLLLALLCVLAAGGGA GEAAILLWTPSVGLVLWAGAFYLFHVQEVNGLYRAQAELQHVLGRAREAQ DLGPEPQPALLLGQQEGDRTKEQ
    • Molecular weight73 kDa including tags
    • Amino acids1 to 423

Specifications

Our Abpromise guarantee covers the use of ab114871 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • ISC1
    • Lyso platelet activating factor phospholipase C
    • Lyso-PAF-PLC
    • Lyso-platelet-activating factor-phospholipase C
    • N-SMase
    • Neutral sphingomyelinase
    • NSMA_HUMAN
    • nSMase
    • NSMASE1
    • Smpd2
    • Sphingomyelin phosphodiesterase 2
    • Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
    see all
  • FunctionConverts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
  • Sequence similaritiesBelongs to the neutral sphingomyelinase family.
  • Cellular localizationMembrane.
  • Information by UniProt

Recombinant Human nSMase protein images

  • 12.5% SDS-PAGE showing ab114871 at approximately 72.64kDa.
    Stained with Coomassie Blue.

References for Recombinant Human nSMase protein (ab114871)

ab114871 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"