Overview

  • Product name
    Recombinant Human NT5M protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMGGRALRVLVDMDGVLADFEGGFLRKFRAR FPDQPFIALEDRRGFWVS EQYGRLRPGLSEKAISIWESKNFFFELEPL PGAVEAVKEMASLQNTDVFICTSPIKMFKYCPYEKYAWVEKYFGP DFL EQIVLTRDKTVVSADLLIDDRPDITGAEPTPSWEHVLFTACHNQHLQLQP PRRRLHSWADDWKAILDSKRPC
    • Molecular weight
      25 kDa including tags
    • Amino acids
      32 to 228
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab113140 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab113140 was purified using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT

General Info

  • Alternative names
    • 3''-nucleotidase
    • 5''
    • 5''(3'')-deoxyribonucleotidase
    • 5'(3')-deoxyribonucleotidase, mitochondrial
    • 5',3'-nucleotidase, mitochondrial
    • Deoxy-5''-nucleotidase 2
    • dNT-2
    • DNT2
    • mitochondrial
    • NT5M
    • NT5M_HUMAN
    see all
  • Function
    Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
  • Tissue specificity
    Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas.
  • Sequence similarities
    Belongs to the 5'(3')-deoxyribonucleotidase family.
  • Cellular localization
    Mitochondrion.
  • Information by UniProt

Recombinant Human NT5M protein images

  • 15% SDS-PAGE analysis of ab113140 (3µg)

References for Recombinant Human NT5M protein (ab113140)

ab113140 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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