Diphosphoinositol polyphosphate phosphohydrolase type 2
Nucleoside diphosphate linked moiety X motif 4
Nudix (nucleoside diphosphate linked moiety X) type motif 4
Nudix motif 4
Nudix type motif 4
NUDT4 (Nudix (nucleoside diphosphate linked moiety X)-type motif 4) is a member of the DIPP subfamily of Nudix proteins which hydrolyze specific diphosphoinositol polyphosphates and diadenosine polyphosphates. NUDT4 cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. It is also able to catalyze the hydrolysis of dinucleoside oligophosphate Ap6A, but not Ap5A.
ab161332 on a 12.5% SDS-PAGE stained with Coomassie Blue.
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