The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Immediate-early response protein NOT
Intermediate early receptor protein
NGFI B/nur77 beta type transcription factor homolog
nuclear receptor of T cells
nuclear receptor related 1
Nuclear receptor subfamily 4 group A member 2
Nur related protein 1 homolog
nur related protein-1, human homolog of
Orphan nuclear receptor NR4A2
Orphan nuclear receptor NURR1
T cell nuclear receptor NOT
T-cell nuclear receptor NOT
Transcriptionally inducible nuclear receptor
Transcriptionally inducible nuclear receptor related
Transcriptionally inducible nuclear receptor related 1
Transcriptionally-inducible nuclear receptor
FunctionTranscriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
Tissue specificityExpressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue.
Sequence similaritiesBelongs to the nuclear hormone receptor family. NR4 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Developmental stageRapidly and only very transiently expressed after cell activation, during the G0-G1 transition of the cell cycle.