Recombinant Human NYREN18 protein (ab162630)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLE CCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNL LETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHN VKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRA AETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRK EYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECL DDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRN YHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRAC DGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQ QILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRV FRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTD EDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENRKSATKK N
    • Amino acids
      1 to 601
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab162630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • BS4
    • NEDD8 ultimate buster 1
    • Negative regulator of ubiquitin like proteins 1
    • Negative regulator of ubiquitin-like proteins 1
    • NUB1
    • NUB1_HUMAN
    • NUB1L
    • NY REN 18
    • NYREN18
    • Renal carcinoma antigen NY-REN-18
    see all
  • Function
    Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
  • Tissue specificity
    Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
  • Sequence similarities
    Contains 3 UBA domains.
  • Cellular localization
    Nucleus. Predominantly nuclear.
  • Information by UniProt

Images

  • ab162630 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab162630 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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