Recombinant human Oncostatin M protein (ab9634)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP13725
    • SpeciesHuman
    • SequenceAAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRRT RPSRKGKRLM TRGQLPR
    • Molecular weight26 kDa
    • Amino acids25 to 252

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    The ED50 as determined by the dose-dependent stimulation of the proliferation of Human TF-1 cells is ≤ 2 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • MGC20461
    • ONCM_HUMAN
    • Oncostatin M
    • Oncostatin-M
    • OSM
    see all
  • FunctionGrowth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
  • Sequence similaritiesBelongs to the LIF/OSM family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant human Oncostatin M protein (ab9634)

ab9634 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. We recommend centrifuging the vial prior to opening, reconstituting this protein with 10-100uL of water, and mixing with gentle pipetting. You should not need a solvent to bring the protein into solution. If you continue to...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"