The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesBest use within three months from the date of receipt of this protein.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.31% Glutathione
Origin Recognition Complex 1
Origin recognition complex subunit 1
Origin recognition complex subunit 1 (yeast homolog) like
Origin recognition complex subunit 1 homolog
Origin recognition complex subunit 1 like
Origin recognition complex subunit 1 like (S. cerevisia
Origin recognition complex subunit 1 S. cerevisiae homolog like
Origin recognition complex, subunit 1 like (yeast)
Replication control protein 1
FunctionComponent of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Sequence similaritiesBelongs to the ORC1 family. Contains 1 BAH domain.
Developmental stageExpression is cell-cycle regulated, it starts to accumulate in mid-G1 phase, reaches a peak at the G1/S boundary, and decreases to a basal level in S phase (at protein level).