Recombinant Human Orexin Receptor 2 protein (ab112299)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionO43614
    • SpeciesHuman
    • SequenceMSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHP KEYE
    • Molecular weight32 kDa including tags
    • Amino acids1 to 54
    • TagsGST tag N-Terminus

Associated products

Specifications

Our Abpromise guarantee covers the use of ab112299 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityuseful for Antibody Production and Protein Array
  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesuseful for Antibody Production and Protein Array
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Glutathione is reduced

General Info

  • Alternative names
    • Hcr tr2
    • Hcrt receptor 2
    • Hcrtr2
    • Hypocretin (orexin) receptor 2
    • Hypocretin receptor 2
    • Hypocretin receptor type 2
    • Orexin 2 receptor
    • Orexin A/Orexin B receptor
    • Orexin receptor 2
    • Orexin receptor type 2
    • Orexin type 2 receptor
    • Ox-2-R
    • Ox2-R
    • Ox2r
    • OX2R_HUMAN
    • Type 2 hypocretin receptor
    • Type 2 orexin receptor
    see all
  • FunctionNonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • DomainThe N-terminal region is required for orexin signaling.
  • Cellular localizationCell membrane.
  • Information by UniProt

Recombinant Human Orexin Receptor 2 protein images

  • ab112299 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

References for Recombinant Human Orexin Receptor 2 protein (ab112299)

ab112299 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab112299.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"