Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ92882
    • SpeciesHuman
    • SequenceMSKPPPKPVK PGEGGQVKVF RALYTFEPRT PDELYFEEGD IIYITDMSDT NWWKGTSKGR TGLIPSNYVA EQAESIDNPL HEAAKRGNLSWLRECLDNRV GVNGLDKAGS TALYWACHGG HKDIVEMLFT QPNIELNQQN KLGDTALHAA AWKGYADIVQ LFLAKGARTD LRNIEKKLAF DMATNAACAS LLKKKQGTDA VRTLSNAEDY LDDEDSDLEH HHHHH
    • Molecular weight25 kDa including tags
    • Amino acids1 to 214
    • TagsHis tag C-Terminus
    • Additional sequence informationOSTF1 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, polypeptide chain containing 222 amino acids (1-214) and having a molecular mass of 25.1 kDa.

Specifications

Our Abpromise guarantee covers the use of ab117673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab117673 is purified by proprietary chromatographic techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.24% Tris, 0.01% DTT, 10% Glycerol

General Info

  • Alternative names
    • bA235O14.1
    • FLJ20559
    • OSF
    • Osteoclast stimulating factor 1
    • Osteoclast-stimulating factor 1
    • Ostf1
    • OSTF1_HUMAN
    • SH3P2
    see all
  • FunctionInduces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
  • Tissue specificityUbiquitously expressed. Present in osteoclasts (at protein level).
  • Sequence similaritiesContains 3 ANK repeats.
    Contains 1 SH3 domain.
  • DomainThe SH3 domain mediates interaction with SMN1.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Recombinant Human OSTF1 protein (ab117673)

ab117673 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"