Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSEFMSAFS EAALEKKLSE LSNSQQSVQT LSLWLIHHRK HSRPIVTVWE RELRKAKPNR KLTFLYLAND VIQNSKRKGP EFTKDFAPVI VEAFKHVSSE TDESCKKHLG RVLSIWEERS VYENDVLEQL KQALYGDKKP RKRTYEQIKV DENENCSSLG SPSEPPQTLD LVRALQDLEN AASGDAAVHQ RIASLPVEVQ EVSLLDKITD KESGERLSKM VEDACMLLAD YNGRLAAEID DRKQLTRMLA DFLRCQKEAL AEKEHKLEEY KRKLARVSLV RKELRSRIQS LPDLSRLPNV TGSHMHLPFA GDIYSED
    • Molecular weight
      38 kDa including tags
    • Amino acids
      1 to 312
    • Tags
      His tag N-Terminus
    • Additional sequence information
      NCBI Accession No.: NP_060640.

Specifications

Our Abpromise guarantee covers the use of ab180347 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    >95% by SDS-PAGE .
    ab180347 was purified using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.0
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.88% Sodium chloride, 0.02% DTT

General Info

  • Alternative names
    • C77387
    • CDKN2B-related protein
    • Cyclin dependent kinase 2B inhibitor related protein
    • Cyclin dependent kinase inhibitor 2B related protein
    • Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein)
    • Cyclin dependent kinase inhibitor related protein
    • Cyclin-dependent kinase inhibitor 2B-related protein
    • FLJ10656
    • HsT3101
    • Hypothetical protein FLJ10656
    • KIAA4077
    • MGC19513
    • MGC29396
    • MGC36325
    • mKIAA4077
    • p15INK4B related protein
    • p15INK4B-related protein
    • Putative uncharacterized protein P15RS
    • Regulation of nuclear pre mRNA domain containing 1A
    • Regulation of nuclear pre-mRNA domain-containing protein 1A
    • RGD1307374
    • RPR1A_HUMAN
    • RPRD1A
    see all
  • Function
    Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
  • Sequence similarities
    Belongs to the UPF0400 (RTT103) family.
    Contains 1 CID domain.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab180347 (3 µg)

References

ab180347 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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