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- SourceEscherichia coli
- Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Purity> 90
Purity was determined to be >90% by densitometry.
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Preparation and Storage
- Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5
- CDK6 inhibitor p18
- CDKN 2C
- CDKN 6
- FunctionInteracts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB.
- Tissue specificityHighest levels found in skeletal muscle. Also found in pancreas and heart.
- Sequence similaritiesBelongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Contains 4 ANK repeats.
Information by UniProt
Recombinant Human p18 INK4c protein images
References for Recombinant Human p18 INK4c protein (ab85605)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"