Recombinant human P70 S6 Kinase beta protein (ab84798)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab84798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific activity: 107nmol/min/mg.
  • Applications

    Western blot

    Functional Studies

  • Form
    Liquid
  • Additional notes

    ab204879 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 70 kDa ribosomal protein S6 kinase 2
    • EC 2.7.11.1
    • KS6B2_HUMAN
    • p70 beta
    • p70 ribosomal S6 kinase beta
    • p70 S6 kinase beta
    • p70 S6K-beta
    • p70 S6KB
    • p70 S6Kbeta
    • p70(S6K) beta
    • p70-beta
    • p70-S6K 2
    • P70S6K2
    • p70S6Kb
    • Ribosomal protein S6 kinase 70kDa, polypeptide 2
    • Ribosomal protein S6 kinase B2
    • Ribosomal protein S6 kinase beta 2
    • Ribosomal protein S6 kinase beta-2
    • Rps6kb2
    • S6 kinase related kinase
    • S6 kinase-related kinase
    • S6K beta
    • S6K beta 2
    • S6K-beta
    • S6K-beta-2
    • S6K2
    • Serine/threonine protein kinase 14 beta
    • Serine/threonine-protein kinase 14B
    • SRK
    • STK14B
    see all
  • Function
    Phosphorylates specifically ribosomal protein S6.
  • Sequence similarities
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt

Images

  • specific activity of ab84798
  • SDS Page analysis of ab84798

References

ab84798 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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