Recombinant Human PACS2 protein (ab161579)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
Description
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Product name
Recombinant Human PACS2 protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLV VFKELEKELISVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQY PHFLKREGNKLQIMLQRRKRYKNRTILGYKTLAAGSISMAEVMQHPSEGG QVLSLCSSIKEAPVKAADIWIASLSSQPIDHEDSTMQAGPKAKSTDNYSE EEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQN FKQKVVALLRRFKVSGEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSP ADVPEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDV FTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARPQNER ANSLDNERCPDARSQLQIHRKTVYDQLNDILISDDQLPENIILVNTSDWQ GQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQRYCNCNSQPPTPVK IAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVARYLGS VDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQL PIAEAMLTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPS GSGTLSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVD YWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATPTM SMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICTARQQQNMLR VLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF -
Amino acids
1 to 889 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab161579 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- 6720425G15Rik
- AW208651
- AW489976
see all -
Function
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. -
Tissue specificity
Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis. -
Sequence similarities
Belongs to the PACS family. -
Cellular localization
Endoplasmic reticulum lumen. Mitochondrion. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab161579 has not yet been referenced specifically in any publications.