Guanine nucleotide binding protein (G protein) beta polypeptide 1
Guanine nucleotide binding protein (G protein) gamma 2
Guanine nucleotide binding protein beta 1 subunit
Guanine nucleotide binding protein G(i) subunit alpha 1
Guanine nucleotide binding protein G(I)/G(O) gamma 2 subunit
Guanine nucleotide binding protein G(I)/G(S)/G(O) subunit gamma 2
Guanine nucleotide binding protein G(I)/G(S)/G(T) beta subunit 1
Guanine nucleotide binding protein G(I)/G(S)/G(T) subunit beta 1
Guanine nucleotide binding protein gamma 2
Platelet activating factor receptor
Transducin beta chain 1
RelevancePlatelet-activating factor (PAF) is a pro-inflammatory lipid mediator possessing a unique 1-O-alkyl-2-acetylsnglycero-3-phosphocholine backbone.
The PAF receptor (PAFR), which belongs to the superfamily of seven transmembrane (7TM), G-protein coupled receptors (GPCRs), transduces pleiotropic functions including cell motility, smooth muscle contraction, and synthesisand release of mediators and cytokines via multiple
heterotrimeric G-proteins. Pharmacological studies have suggested that PAF functions in a variety of settings including allergy, inflammation, neural functions, reproduction, and atherosclerosis.
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction
Cellular localizationPAFR: Cell membrane; Multi-pass membrane protein
GNG2 Cell membrane; Lipid-anchor; Cytoplasmic side
References for Recombinant Human PAFR +Gia1ß1?2 fusion co-expressed protein (ab90726)
has not yet been referenced specifically in any publications.
Publishing research using ab90726? Please let us know so that we can cite the reference in this datasheet.
Concentration of lot no. is
Concentration not available for this lot.
Find concentration of your lot:
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"