Recombinant Human PAI1 + PLAT protein (ab92549)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab92549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    Human PAI1 stable mutant is reacted with an excess of Human sc-PLAT at physiological pH. The resulting 1:1 molar complex is purified from the remaining PLAT by cobalt metal affinity chromatography resin.
  • Form
    Liquid
  • Additional notes
    Spectrophotometric data: e0.1%=1.56
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.4M HEPES, 0.1M Sodium chloride, pH 7.4

General Info

  • Alternative names
    • Alteplase
    • PAI 1
    • PLANH1
    • Plasminogen activator inhibitor 1
    • PLAT
    • Reteplase
    • t PA
    • t plasminogen activator
    • tPA
    see all
  • Relevance
    PAI1 acts as "bait" for tissue plasminogen activator (TPA), urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. TPA: This converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events.
  • Cellular localization
    Secreted protein; extracellular space.

Recombinant Human PAI1 + PLAT protein images

  • 10% SDS-PAGE
    Lane 1: ab92549 (3µg) Reduced
    Lane 2: ab92549 (3µg) Non-Reduced

References for Recombinant Human PAI1 + PLAT protein (ab92549)

ab92549 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab92549.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up