Recombinant Human PAI1 + PLAU protein (ab92553)

Overview

  • Product name
    Recombinant Human PAI1 + PLAU protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab92553 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    Human PAI1 stable mutant is reacted with an excess of Human PLAU at physiological pH. Excess PLAU is removed from the resulting 1:1 molar complex by immobilized benzamidine resin.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1M Sodium chloride, 0.1M HEPES, pH 7.4

General Info

  • Alternative names
    • ATF
    • Endothelial plasminogen activator inhibitor
    • PAI
    • PAI 1
    • PLANH1
    • Plasminogen activator inhibitor 1
    • Plasminogen activator urinary
    • Plasminogen activator urokinase
    • PLAU
    • Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1
    • Serpin E1
    • Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1
    • SERPINE1
    • u PA
    • U plasminogen activator
    • UPA
    • URK
    • Urokinase type plasminogen activator
    see all
  • Relevance
    PAI1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. PLAU specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
  • Cellular localization
    Secreted

References

ab92553 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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