The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. Human PAI1 stable mutant is reacted with an excess of Human PLAU at physiological pH. Excess PLAU is removed from the resulting 1:1 molar complex by immobilized benzamidine resin.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1
Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1
U plasminogen activator
Urokinase type plasminogen activator
RelevancePAI1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.
PLAU specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
References for Recombinant Human PAI1 + PLAU protein (ab92553)
has not yet been referenced specifically in any publications.
Publishing research using ab92553? Please let us know so that we can cite the reference in this datasheet.
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