Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab60754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Form
    Liquid
  • Additional notes

    ab204849 (AKT1 peptide) can be utilized as a substrate for assessing kinase activity

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • EC 2.7.11.1
    • KIAA1264
    • MGC26232
    • p21 activated kinase 7
    • p21 protein (Cdc42/Rac)-activated kinase 7
    • p21(CDKN1A) activated kinase 7
    • p21-activated kinase 5
    • p21-activated kinase 7
    • PAK 5
    • PAK 7
    • PAK-5
    • PAK-7
    • PAK5
    • PAK7
    • PAK7_HUMAN
    • Protein kinase PAK5
    • Serine/threonine protein kinase PAK 7
    • Serine/threonine-protein kinase PAK 7
    see all
  • Function
    The activated kinase acts on a variety of targets.
  • Tissue specificity
    Predominantly expressed in brain.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 CRIB domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated when activated by CDC42/p21.
  • Information by UniProt

Images

  • Sample Kinase Activity Plot.
  • ab60754 on SDS-PAGE, MW ~130kDa.

References

ab60754 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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