Recombinant Human PANK1 protein (ab153362)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
Description
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Product name
Recombinant Human PANK1 protein
See all PANK1 proteins and peptides -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MKLINGKKQTFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRK YLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPSCAMHRFIQMGS EKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVD SVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVY SKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLV KDIYGGDYERFGLQGSAVASSFGNMMSKEKRDSISKEDLARATLVTITNN IGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALF LEHEGYFGAVGALLELFKMTDDK -
Amino acids
1 to 373 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab153362 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- coaA
- hPanK
- hPanK1
see all -
Function
Plays a role in the physiological regulation of the intracellular CoA concentration. -
Tissue specificity
Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle. -
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. -
Sequence similarities
Belongs to the type II pantothenate kinase family. -
Domain
The N-terminal extension, present in isoform 1 may be the regulatory domain. -
Cellular localization
Cytoplasm. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab153362 has not yet been referenced specifically in any publications.