Recombinant human PARP9 protein (ab79665)

Overview

  • Product nameRecombinant human PARP9 protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab79665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific Activity: 196 U/mg.
  • Applications

    SDS-PAGE

    Functional Studies

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • ADP-ribosyltransferase diphtheria toxin-like 9
    • ARTD9
    • AW214463
    • B aggressive lymphoma protein
    • Bagl
    • BAL
    • BAL1
    • BC003281
    • DKFZp666B0810
    • DKFZp686M15238
    • EC 2.4.2.30
    • FLJ26637
    • FLJ35310
    • FLJ41418
    • FLJ43593
    • MGC:7868
    • MGC156739
    • MGC7868
    • OTTMUSP00000028034
    • PARP 9
    • PARP-9
    • Parp9
    • PARP9_HUMAN
    • Poly (ADP ribose) polymerase family member 9
    • Poly [ADP-ribose] polymerase 9
    • RGD1307534
    see all
  • FunctionInvolved in inducing the expression of IFN-gamma-responsive genes.
  • Tissue specificityExpressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form. Most abundantly expressed in lymphomas with a brisk host inflammatory response. In diffuse large B-cell lymphomas tumors, expressed specifically by malignant B-cells.
  • Involvement in diseaseNote=Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration. May therefore be involved in promoting B-cell migration and dissemination of high-risk DLB-CL tumors.
  • Sequence similaritiesContains 2 Macro domains.
    Contains 1 PARP catalytic domain.
  • Cellular localizationCytoplasm > cytosol. Nucleus. Shuttles between the nucleus and the cytosol. Export to the cytosol depends on the interaction with DTX3L.
  • Information by UniProt

Recombinant human PARP9 protein images

  • SDS-PAGE showing ab79665 at approximately 119kDa (4µg).

References for Recombinant human PARP9 protein (ab79665)

ab79665 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

The lab let me know that the protein is a (proprietary tag)-PARP9-His. It has the proprietary tag on the N-terminus and a C-terminal 6x His-tag.

I hope this helps explain your results.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"