The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 1.000 Eu/µg
>95% by SDS-PAGE .
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).
It is recommended to reconstitute the lyophilized product in deionized water to a final concentration of 1 mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing.
Programmed cell death 1
Programmed cell death 1 protein
Programmed cell death protein 1
Protein PD 1
Systemic lupus erythematosus susceptibility 2
Possible cell death inducer, in association with other factors.
Involvement in disease
Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
SDS-PAGE analysis of ab180060 in DTT-reduced (lane 1) and non-reduced (lane 2) conditions. Gel stained overnight with Coomassie Blue. As a result of different glycosylation, DTT-reduced protein migrates as 55-66 kDa and non-reduced protein migrates as 110-140 kDa.
has not yet been referenced specifically in any publications.
Publishing research using ab180060? Please let us know so that we can cite the reference in this datasheet.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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