Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      86 kDa including tags
    • Amino acids
      1 to 536

Associated products

Specifications

Our Abpromise guarantee covers the use of ab125652 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity of ab125652 was determined to be 89 nmol/min/mg.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 90 % Densitometry.
    Purity was determined to be >90% by densitometry.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 5''-cyclic nucleotide phosphodiesterase 1B
    • 63 kDa Cam PDE
    • 63 kDa Cam-PDE
    • Calcium/calmodulin dependent 3' 5' cyclic nucleotide Phosphodiesterase 1B
    • Calcium/calmodulin stimulated cyclic nucleotide phosphodiesterase
    • Calcium/calmodulin-dependent 3''
    • Calmodulin stimulated phosphodiesterase PDE1B1
    • Cam PDE 1B
    • Cam PDE1B
    • Cam-PDE 1B
    • PDE 1B
    • PDE1B
    • PDE1B_HUMAN
    • PDE1B1
    • PDES 1B
    • PDES1B
    • Phosphodiesterase 1B
    • Phosphodiesterase 1B calmodulin dependent
    • Presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B
    see all
  • Function
    Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
  • Sequence similarities
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab125652.
  • The specific activity of ab125652 was determined to be 89 nmol/min/mg by Phosphodiesterase Assay.

References

ab125652 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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