Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      85 kDa including tags
    • Amino acids
      654 to 1112
    • Tags
      GST tag N-Terminus

Associated products

Specifications

Our Abpromise guarantee covers the use of ab125784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity of ab125784 was determined to be 156 nmol/min/mg.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 70 % Densitometry.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C.

    pH: 7.50
    Constituents: 0.002% PMSF, 0.005% DTT, 0.79% Tris HCl, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 5''-cyclic phosphodiesterase B
    • Adipocyte cAMP phosphodiesterase cGMP inhibited
    • AI847709
    • cAMP Phosphodiesterase, adipocyte, cGMP-inhibited
    • CGI-PDE B
    • CGIP1
    • CGIPDE B
    • CGIPDE1
    • cGMP inhibited 3 5 cyclic phosphodiesterase B
    • CGMP inhibited cAMP phophodiesterase
    • cGMP-inhibited 3''
    • Cyclic GMP inhibited phosphodiesterase B
    • Cyclic GMP-inhibited phosphodiesterase B
    • Cyclic nucleotide phosphodiesterase
    • HcGIP1
    • HcGIP1, rat, homolog of
    • Pde3b
    • PDE3B_HUMAN
    • Phosphodiesterase 3B
    • Phosphodiesterase 3B cGMP inhibited
    see all
  • Function
    Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism.
  • Tissue specificity
    Abundant in adipose tissues.
  • Sequence similarities
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab125784.
  • Sample assay showing the specific activity of ab125784 to be 156 nmol/min/mg.

References

ab125784 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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